Hi, my son, Isaac, was diagnosed with Juvenile Pilocytic Astrocytoma in January 2006 just before he turned 7 years old. His tumor was in the hypothalamus/optic chaism region. After a biopsy, he started chemo (carboplatin/vincristine). Two months later, his tumor grew over 2cm and spread throughout his brain and spine. After another biopsy to confirm diagnosis, Isaac had whole brain/spine radiation due to the severity of his symptoms (no one felt we had time to try another chemo). He finished radiation in June 2006. From July 2009 to July 2010, Isaac was on chemo again, this time with Avastin & Irinotecan (CPT-11). This past March, Isaac needed to start chemo again. We decided to try a phase 1 clinical trial. He is on AZD6244 (Selumetinib). He is doing well. It is pretty easy on him and he just had an MRI that showed that the tumors have less enhancement and are slightly less “full”. Isaac is now 13 years old and will be entering the 8th grade. It’s been a long road but overall, we are doing fairly well. Here is his website: http://www.caringbridge.org/visit/isaachatfield Nice to “meet” you all.